Normally, a callus will form on any part of the skin exposed to excess friction over a long period of time. Rubbing that is too frequent or forceful will cause blisters, as opposed to calluses, to form. However, excessive formation may sometimes lead to other problems, such as a skin ulceration or infection, or cause the affected person to try to offload the affected painful area, which can place excessive stress on the asymptomatic side. Ĭalluses are generally not harmful and help prevent blisters, as well as offering protection. Some degree of callus, such as on the bottom of the foot, is normal. Since repeated contact is required, calluses are most often found on the feet and hands, but they may occur anywhere on the skin. Calluses (plantar in right foot and medial in left foot)Ī callus ( pl.: calluses) is an area of thickened and sometimes hardened skin that forms as a response to repeated friction, pressure, or other irritation.